A UNIQUE HMG-BOX DOMAIN OF MOUSE MAELSTROM BINDS STRUCTURED RNA BUT NOT DOUBLE STRANDED DNA.




Resistance to anti-EGFR therapies in metastatic colorectal cancer: underlying mechanisms and reversal strategies

Abstract Cetuximab and panitumumab are monoclonal antibodies (mAbs) against epidermal growth factor receptor (EGFR) that are effective agents for metastatic colorectal cancer (mCRC).Cetuximab can prolong survival by 8.2 months in RAS wild-type (WT) mCRC patients.Unfortunately, resistance to targeted therapy impairs clinical Top Nail Coats use and e

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Semimetallization induced Hall anomaly in doped polymers

Hall anomaly related to deviations in Hall copyright concentrations have always been recognized as signs of charge incoherence in organic semiconductors, which lack ordered lattices.In this paper, we show that the Hall copyright Candles concentration anomaly in doped polymers might be a result of semimetallization.Based on the observation of semime

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